I think it could be done right, but like you said, no network would likely take the risks involved with the kind of show Firefly was. Heroes and Lost are rather edgy, but the built-in prejudice against space sci-fi would put Firefly in a different category (even though all three shows are technically sci-fi/fantasy).
I'm still a Browncoat for life, though.
![Wink :wink:](./images/smilies/icon_wink.gif)